THOMAS, SIMON,PULE, MARTIN,SMITH, PAUL,GANNON, ISAAC,BALLAND, WILLIAM
申请号:
CA3082265
公开号:
CA3082265A1
申请日:
2018.11.12
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to an engineered cell which comprises; (i) a chimeric antigen receptor (CAR) or a transgenic T-cell receptor (TCR); and (ii) one or more engineered polynucleotides which encode one or more enzymes which are capable of synthesising a therapeutic small molecule when expressed in combination in the cell.