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Modified globin proteins with altered electron transport pathway
专利权人:
Christopher Eric Cooper
发明人:
Christopher Eric Cooper,Michael Thomas Wilson,Brandon Jon Reeder
申请号:
US12452075
公开号:
US08609814B2
申请日:
2008.06.26
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a modified porphyrin-based oxygen-carrying protein, such as haemoglobin, which has been found, in its unmodified state to have a low affinity site of electron transfer and a high affinity electron transfer between a reductant and ferryl haem iron via one or more protein amino acids. The invention provides such proteins that comprise a modification to enhance this pathway.
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