The present invention relates to a therapeutic composition or bone disease prevention for promoting hair growth, including the same, and peptides derived from noggin, for improving skin condition, or an anti-inflammatory,. It has a function that is similar or identical to the Hitonogin natural, it is compared to the noggin, shows a better stability, peptide noggin of the present invention (Noggin) derived from, are very good in skin permeability. In accordance with the present invention, the growth factor-related symptoms, ie, hair loss, skin improvement, treatment or wounds, growth factor overexpression symptoms, prevention, or composition containing as an active ingredient a peptide of the present invention has excellent improvement I will demonstrate efficacy. Therefore, activity and stability superior peptide of the present invention described above may be applied very advantageously in pharmaceutical, quasi-drugs and cosmetics.本発明は、ノギン由来のペプチド及びこれを含む発毛促進用、皮膚状態改善用、抗炎症、又は骨疾患予防又は治療用組成物に関する。本発明のノギン(Noggin)由来のペプチドは、天然のヒトノギンと同一あるいは類似した機能を有し、ノギンと比較し、より優れた安定性を示し、皮膚透過度に非常に優れている。本発明によると、本発明のペプチドを有効成分として含む組成物は、成長因子関連症候、即ち、脱毛、皮膚改善、又は創傷、成長因子過発現症候の治療、予防、又は改善に非常に優れた効能を発揮する。したがって、上述の本発明のペプチドの優れた活性及び安定性は、医薬、医薬外品及び化粧品に非常に有利に適用することができる。
