LEE, JIN HWA,이진화,KIM, JONG YUP,김종엽,KIM, JEONG MIN,김정민,AHN, KWANG WOO,안광우
申请号：
KR1020127032531
公开号：
KR1020130072221A
申请日:
2011.05.13
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A (+)-3-hydroxymorphinan-based polycyclic derivative is provided to be used as a neuroprotectant for treating Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and ischemic stroke. CONSTITUTION: A compound is denoted by chemical formula Ia and Ia'. A pharmaceutical composition for preventing or treating neurodegenerative diseases contains the compound and a pharmaceutically acceptable carrier. The compound is used for manufacturing a drug for preventing neurodegenerative diseases.본 발명은, 알츠하이머병, 파킨슨병, 헌팅턴병, 근위축성 측색 경화증, 및 허혈성 뇌졸중을 비롯한 신경변성 질환에 대한 신경보호제로서 효과적인 화학식 I의 (+)-3-하이드록시모르피난계 다환 유도체에 관한 것이다.
