Use of a composition comprising at least one fluoroalkene having the Formula I: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ XCF z R 3-z €ƒ€ƒ€ƒ€ƒ€ƒ(I) where X is a C 2 to C 5 unsaturated, substituted or unsubstituted radical, each R is independently Cl, F, Br, I or H, and z is 1 to 3, as an extractant for biologically-active compounds, fragrances or flavours.本發明揭示四氟丙烯,尤其係(HFO-1234)在包括製冷設備在內之多種應用中的各種用途。此等材料通常可用作加熱及冷卻致冷劑、用作發泡劑、用作氣溶膠推進劑、用作溶劑組合物、以及用作滅火劑及抑燃劑。