Burke David J.,Buckley Shaun E.,Lehrman Sherwood Russ,O'Connor Barbara Horsey,Callaway James,Phillips Christopher,OConnor Barbara Horsey,Phillips Christo
申请号:
SI200432441
公开号:
SI2236154T1
申请日:
2004.02.09
申请国别(地区):
SI
年份:
2018
代理人:
摘要:
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.