가톨릭대학교 산학협력단;CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION;CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATIONFOUNDATION
发明人:
JU, JI HYEON,주지현,KIM, YOUNG KYUN,김영균,YI, HYO JU,이효주
申请号：
KR1020130053356
公开号：
KR1020130126549A
申请日:
2013.05.10
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
The present invention relates to a pharmaceutical composition containing a minicircle vector which expresses tumor necrosis factor receptor type 2 (TNFR2) for treating autoimmune diseases. The pharmaceutical composition of the present invention contains: (a) a gene expression cassette containing a promoter, a gene encoding TNFR2 proteins or a fragment containing extracellular region of TNFR2, and a terminator； b) a site-specific recombinant region located at the outside of the gene expression cassette； and a non-viral vector which does not contain a replication origin and a selection marker gene as active ingredients.본 발명은 TNFR2를 발현하는 미니서클 벡터를 포함하는 자가 면역 질환 치료용 약학 조성물에 관한 것이다.
