PROBLEM TO BE SOLVED: To provide a vaccine for the prophylaxis and/or therapy of HTLV-1 related disease which can efficiently induce HBZ specific CTL.SOLUTION: The present invention provides a vaccine for the prophylaxis and/or therapy of human T-cell leukemia virus type 1 (HTLV-1) related disease, comprising peptides comprising at least one amino acid sequence selected from the group consisting of a specific sequence, another specific sequence, still another specific sequence, and further another specific sequence, in amino acid sequences of HBZ protein of HTLV-1, as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】HBZ特異的CTLをより効率的に誘導できる、HTLV-1関連疾患の予防及び/又は治療用ワクチンを提供する。【解決手段】HTLV-1のHBZタンパク質のアミノ酸配列中、ある特定の配列、他の特定の配列、また他の特定の配列、及びさらに他の特定の配列からなる群より選択される少なくとも1種のアミノ酸配列を含むペプチドを有効成分として含む、ヒトT細胞白血病ウイルス1型(HTLV-1)関連疾患の予防及び/又は治療用ワクチン。【選択図】なし