A system and method for providing Anal Perineal Prostate Vaginal Pelvic Floor contrast therapy are presented. The system may comprise a human interface device, fluid tubing, a pump, and a reservoir. The system may be operable to apply any combination of heat, cold, and pressurized compression to a therapy recipient and demonstrates particular utility for treating anal-prostate-perineal and vaginal areas. The system may be operable to impart a desired therapy temperature to the human interface device and to expand a membrane containing a therapy fluid. The expanded membrane may conform to the contours of a therapy site. Operation of the human interface device may be controlled using a remote-control device. The therapy recipient may be able to control the temperature of the fluid circulating through the membrane and may be able to control the pressure of the fluid within the membrane.