BOTANA LOPEZ, LUIS MIGUEL,ALONSO LOPEZ, EVA,VALE GONZALEZ, CARMEN
申请号：
EP10824499
公开号：
EP2491927A4
申请日:
2010.09.29
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention is in the field of biomedicine. Specifically, it relates to the use of a spirolide compound with the chemical structure:for preparing a drug for the prevention and/or treatment of a pathology related to the increase in β-amyloid protein and/or hyperphosphorylation of tau protein compared to control, where said spirolide compound is administered in the amount necessary to reach a concentration in the serum of equal to or less than 50 nM. The amount administered is preferably the amount necessary to reach a concentration in the serum of between 0.5 nM and 50 nM.
