HYUN-JOO LEE,DONG-HOON KIM,TAE-KYUN KIM,YOUNG-AE YOON,JAE-YOUNG SIM,MYUNG-HUN CHA,EUN-JUNG JUNG,KYOUNG-KYU AHN,TAI-AU LEE
申请号:
PT12750114
公开号:
PT2678332T
申请日:
2012.02.24
申请国别(地区):
PT
年份:
2016
代理人:
摘要:
The present invention provides a diaminopyrimidine derivative or its pharmaceutically acceptable salt, a process for the preparation thereof, a pharmaceutical composition comprising the same, and a use thereof. The diaminopyrimidine derivative or its pharmaceutically acceptable salt functions as a 5-HT4 receptor agonist, and therefore can be usefully applied for preventing or treating dysfunction in gastrointestinal motility, one of the gastrointestinal diseases, such as gastroesophageal reflux disease (GERD), constipation, irritable bowel syndrome (IBS), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, or diabetic gastric atony.