PHARMACEUTICAL COMPOSITION, DRESSING AND METHOD FOR TREATING SKIN LESION, INTERMEDIATE COMPOSITION AND PROCESS FOR PREPARING SAID DRESSING, AND USE OF CERIUM SALT ASSOCIATED WITH A COLLAGEN MATRIX
The present invention refers to a pharmaceutical composition for treating skin lesion, comprising a cerium salt on a collagen matrix and a dermatologically acceptable carrier. In addition, the present invention also provides an intermediate composition for preparing a dressing for treating skin lesion and a process for preparing such dressing by lyophilizing said intermediate composition. The present invention also refers to a dressing for treating skin lesion, comprising a cerium salt on a collagen matrix, as well as to the use of a cerium salt associated with collagen in the preparation of the pharmaceutical composition or dressing according to the present invention. Another embodiment of the present invention is a method for treating skin lesion by applying such pharmaceutical composition or dressing on said skin lesion. The composition or dressing of the present invention can be used in topical applications in a variety of lesion types, such as skin lesions involving the release of toxins related to microbial proteins on human or animal organisms, or those so-called HSPs (heat shock proteins) burns which involve burned skin toxin formation or LPC (lipoprotein complex) chronically ulcerate skin lesions in which there is an overproduction of proteinase skin lesions of difficult resolution, in which control of exudate overproduction is required and critically infected or colonized skin lesions.La présente invention concerne une composition pharmaceutique destinée à traiter une lésion cutanée, comprenant un sel de cérium sur une matrice de collagène et un véhicule dermatologiquement acceptable. De plus, la présente invention concerne une composition intermédiaire pour préparer un pansement destiné à traiter une lésion cutanée et un procédé de préparation dudit pansement par lyophilisation de ladite composition intermédiaire. La présente invention concerne également un pansement destiné à traiter une lésion cutanée, comprenant un sel de cérium sur une matrice de coll
