A chemical entity as a spleen tyrosine kinase (Syk) inhibitor is disclosed, i.e., a chemical entity comprising 6  ̄ (- 1R, 2S)} 2  ̄ aminocyclohexylamino} 7  ̄ fluoro  ̄ 4  ̄ (1  ̄ methyl  ̄ 1H  ̄ pyrazole  ̄ 4  ̄ YL) 1H  ̄ pyrrolo [3,4  ̄ C] pyridine  ̄ 3 (2H)} one and some solid forms thereof are disclosed. Methods of using these chemical entities to treat diseases such as cancer are also disclosed.公開了作爲脾酪氨酸激酶(SYK)抑制劑的化學實體,即,包含6‑((1R,2S)‑2‑氨基環己基氨基)‑7‑氟‑4‑(1‑甲基‑1H‑吡唑‑4‑基)‑1H‑吡咯并[3,4‑c]吡啶‑3(2H)‑酮的化學實體及其某些固態形式。還公開了使用這些化學實體治療諸如癌症的病症的方法。