The Regents of the University of California;加利福尼亞大學董事會
发明人:
KIPPS, Thomas, J.,YU, Jian
申请号：
HK18110442
公开号：
HK1250999A1
申请日:
2018.08.14
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
Provided herein are, inter alia, methods of identifying agents that are capable inhibiting the binding (e.g., coupling) between a ROR1 protein and a ROR2 protein. By interfering with ROR1-ROR2 coupling (binding) the agents identified using the methods provided herein inhibit non-canonical Wnt5a signaling. Thus, the agents identified by the methods provided herein may, inter alia, be useful for cancer diagnosis and therapy.
