Dhong Hyun Lee,Nils H. Thoennissen,H. Phillip Koeffler
申请号：
US13512855
公开号：
US20120238532A1
申请日:
2010.11.30
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention describes the combination of cucurbitacin (CuB) with methotrexate (MTX) for the treatment of cancers, including osteosarcoma. It was discovered that CuB and MTX have synergistic activity against osteosarcoma, which reduces toxicities associated with both chemotherapeutic agents. The present invention also describes the use of CuB for the treatment of osteosarcoma.
