The Regents of the University of Colorado; a Body Corporate
发明人:
Martha Karen Newell-Rogers,Evan Newell
申请号:
US16543878
公开号:
US20200069766A1
申请日:
2019.08.19
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to methods for modulating the immune function through targeting of CLIP molecules. The result is wide range of new therapeutic regimens for treating, inhibiting the development of, or otherwise dealing with, a multitude of illnesses and conditions, including autoimmune disease, cancer, Alzheimer's disease, allergic disease, transplant and cell graft rejection, HIV infection and other viral, bacterial, and parasitic infection, and AIDS. Methods are also provided for preparing a peptide having the property of being able to displace CLIP by feeding one or more peptide sequences into software that predicts MHC Class II binding regions in an antigen sequence and related products.