Reinforced esophageal heat transfer devices are disclosed. An example reinforced esophageal heat transfer device includes a distal end configured for nasopharyngeal or oropharyngeal insertion into an esophagus of a subject, a proximal end including an inlet port and an outlet port, a heat transfer region between the distal end and the proximal end, one or more lumens configured for providing a fluid path for flow of a heat transfer medium to and from the heat transfer region, and one or more reinforcing elements configured for reinforcing the one or more lumens to enable the heat transfer medium to flow through the fluid path via negative pressure.