Compounds containing these compounds and their use in the treatment of kidney disease. In addition, a method for preparing the same claim 1 is provided: formula compound (1), wherein: R1 is tar, cyclomequine, cyclomethylclalquilo, alcoxi, alcohydro, cyclomethoxy, cyclomethoxy, haloalkylation, haloalkylation, haloalkylation, halocyclomethoxy, halocycloformyl, halomethylcyclomethoxy, halomethylcycloquinol Halogenated cyclohexane tar, epoxy carbide, cyclohexane, oxycarbide, halogenated cyclohexane, cyanogen, arilo, alternative arilo, isocyano or isocyanosaid substituted aryl and substituted heteroaryl are substituted with one to three substituents independently selected from alkyl, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, cycloalkylalkoxy, cycloalkylalkoxyalkyl, cycloalkoxy, cycloalkoxyalkyl, alkylcycloalkylalkyl, halocycloalkyl, halocycloalkylalkyl, halogen, cyano, haloalkyl, alkoxy, alkoxyalkyl , haloalkoxy, alkoxyalkoxy, alkoxyalkoxyalkyl, amino and substituted amino, said substituted amino is substituted by one or two substituents independently selected from alkyl, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, alkylcycloalkylalkyl, hydroxyalkyl and alkoxyalkyl；R2 is hydrogen, alkyl, haloalkyl, alkoxy, cycloalkyl, cyano or halogen； R3 is hydrogen, alkyl, haloalkyl, alkoxy, cycloalkyl, cyano or halogen； R4 is hydrogen, alkyl, haloalkyl, alkoxy, cycloalkyl, cyano or halogen； R5 is hydrogen, alkyl, haloalkyl, alkoxy, cycloalkyl, cyano or halogen； R6 is hydrogen, alkyl, haloalkyl, alkoxy, cycloalkyl, cyano or halogen； R7 is hydrogen, alkyl or cycloalkyl； R8 is hydrogen, alkyl or cycloalkyl； R9 is hydrogen, alkyl or cycloalkyl； R10 is hydrogen, alkyl or cycloalkyl； or R9 and R10 together with the carbon, to which they are attached, form a cycloalkyl or a heterocycloalkyl； R11 is hydrogen,Tar or cyclopentadiene； R12 is hydrogen, tar, cyclopentadiene or - C (o) - R13； R13 is tar, cyclopentadiene, cyclopentadiene, epoxy, epoxy, cyclopentyloxy, halogenated cyclopentadie
