Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and use thereof

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专利权人:

Memory Pharmaceuticals Corporation

发明人:

Wenge Xie,Brian Herbert,Richard Schumacher,Truc Nguyen,Jianguo Ma,Carla Gauss,Ashok Tehim

申请号：

US13838088

公开号：

US08691841B2

申请日:

2013.03.15

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

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