PURPOSE: A product containing Lactobacillus johnsonii HY7041 with an anti-inflammatory function is provided to induce the expression of Foxp3(Forkhead box p3) transcriptional regulator and to reduce IL-12 expression. CONSTITUTION: Lactobacillus johnsonii HY7041(deposit number: KCTC 11958BP) has an anti-inflammatory function by enhancing the expression of Foxp3(Forkhead box p3) transcriptional regulator in the regulatory T cells(Tregs). The strain enhances the expression of the anti-inflammatory cytokine IL-10. The strain reduces IL-12 expression. A pharmaceutical composition for anti-inflammation contains the strain as an active ingredient. Fermented milk contains the strain as an active ingredient. A health functional food contains the strain as an active ingredient.본 발명은 항염증 효능을 갖는 락토바실러스 존소니(Lactobacillus johnsonii) HY7041 및 이를 유효성분으로 함유하는 제품에 관한 것으로서, 염증성 질환의 치료 및 예방과 더불어 항염증 효능을 위한 약학적 조성물, 발효유, 건강기능 식품 등으로 이용될 수 있다.
