CHOI JOON HO,최준호,CHO WON KYUNG,조원경,ROH JONG HWA,노종화,SHIN KWANG HYUN,신광현,WOO BYOUNG YOUNG,우병영,KIM MIN SOO,김민수,PARK EUN SIL,박은실,PARK JAE HONG,박제홍,LEE KI WHA,이기화,PARK MI YOUNG,박미영,PARK YOUNG HO,박영호
申请号:
KR1020180044818
公开号:
KR1020190121472A
申请日:
2018.04.18
申请国别(地区):
KR
年份:
2019
代理人:
摘要:
The present invention relates to a pharmaceutical composition which contains (R)-N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide as a first component and a vinylpyrrolidone polymer as a second component, wherein a composition of the present invention has a long-term delay in the crystallization of a compound represented by chemical formula 1.COPYRIGHT KIPO 2020(R)-N-[1-(3,5-다이플루오로-4-메테인설폰일아미노-페닐)-에틸]-3-(2-프로필-6-트라이플루오로메틸-피리딘-3-일)-아크릴아마이드를 제1 성분으로 포함하고, 비닐피롤리돈계 폴리머를 제2 성분으로 포함하는 약학 조성물에 관한 것으로, 본 발명의 조성물은 화학식 1로 표시되는 화합물의 결정형성이 장기간 지연되는 제형 특성을 가진다.