A medical solution packaging assembly comprising a medical solution container that houses a medical solution comprising a semi-permeable material including one or more surface that is at least partially permeable to air molecules and has low permeability to vapor molecules of the medical solution, wherein the medical solution container is configured to inflate beyond its original volume. The assembly further comprising a packaging comprising one or more surface within which the solution container resides； a compressing mechanism configured to apply external force onto at least one surface of the medical solution container or limit the volume to which the medical solution container inflates, wherein a volume of air ingress from an external environment of the medical solution container is less than that which would occur without the compressing mechanism.
