Cell Ideas Pty Ltd;Northern Sydney Local Health District
发明人:
Vesey Graham,Davey Ross Arthur,Weir Christopher John
申请号:
NZ62970013
公开号:
NZ629700A
申请日:
2013.12.24
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Disclosed is a method for producing a vaccine for the treatment or prevention of cancer, the vaccine comprising solubilized components of a cancer cell or cancer-associated cell, and a non-mammalian polypeptide selected from streptavidin, avidin or neutravidin or a fragment or variant thereof which is capable of binding a mammalian protein, the method comprising exposing a biological sample comprising at least one cancer cell or cancer- associated cell to an ionic detergent, a reducing agent, and a non-mammalian polypeptide capable of binding a mammalian protein, to produce a solubilized biological sample comprising components from the cancer cell or cancer-associated cell, and a non- mammalian polypeptide capable of binding a mammalian protein.