Sam Possemiers,Cindy Duysburgh,Iris Pinheiro,Selin Bolca,Pieter Van Den Abbeele,Massimo Marzorati
申请号:
US16311431
公开号:
US20190209516A1
申请日:
2017.06.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to the use of carotenoids, in particular a microbial carotenoid compound of formula I, such as methyl-glycosyl-apo-8′;-lycopenoate or glycosyl-apo-8′;-lycopene, for restoring and/or maintaining a health-beneficial gut microbial composition in a subject. The invention further provides the use of said compound in the treatment of disorders associated with a disturbed intestinal barrier integrity, such as for example irritable bowel syndrome. Further, a compound or composition comprising a microbial carotenoid compound is disclosed for use in the prevention and/or treatment of disorders associated with disturbed intestinal barrier integrity.