A resettable dose setting mechanism for a drug delivery device comprising a driver for driving a spindle of the drug delivery device is provided. Said driver comprises a first component (44; 207) and a second component (46; 212) rotationally coupled to said first component (44; 207). During resetting of said drug delivery device, said first component (44; 207) is rotationally decoupled from said second component (46; 212).