Donmienne Doen Mun Leung,Ling Liu,Jirong Lu,Ying Tang,Jianghuai Xu
申请号:
US14709511
公开号:
US09580499B2
申请日:
2015.05.12
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to compounds that bind to human vascular endothelial growth factor receptor-2 (VEGFR2) and human angiopoietin-2 (Ang2), and may be useful for treating cancer, especially solid tumors driven by VEGFR2 and Ang2, including gastric, hepatocellular carcinoma, ovarian, colorectal, non-small cell lung, biliary tract, and breast cancers.