TAYLOR, DOUG,MCCLAIN, JAMES B.,SMOKE, CLINT,COLE, MIKE,DEYOUNG, JAMES
申请号:
CA2615452
公开号:
CA2615452C
申请日:
2006.07.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
A method for depositing a coating comprising a polymer and pharmaceuticalagent on a substrate, comprising the following steps: discharging at least onepharmaceutical agent in a therapeutically desirable morphology in dry powderform through a first orifice; discharging at least one polymer in dry powderform through a second orifice; depositing the polymer and/or pharmaceuticalparticles onto said substrate, wherein an electrical potential is maintainedbetween the substrate and the pharmaceutical and/or polymer particles, therebyforming said coating; and sintering said coating under conditions that do notsubstantially modify the morphology of said pharmaceutical agent.