This relates to the technical field of the production of Derivatives of Aquaculture, More specifically to a system and Method for Automated and sustainable production from Aquaculture (preferably the creation of tilapia), that aims to produce d Meat and Fish for food, among other applications in the field of Aquaculture.The system consists of a Greenhouse (2), where in its interior contains a rectangular Dam (1) divided into departments with a Production Area of the Fish (1a), where in its interior is a system formed by Oxygen diffusers Air Disc (3) or by MANGUER As for the Porous micro Air Compressor, radial (3a)And a decantation area (1b) divided into three Dikes, which are equipped with a system of biofilter (4) through the Floating aquatic macrophytes (b) for the removal of nitrogen compounds from water.This is a system of Filters and Recirculation of water in a closed circuit, which can be heated through solar heat and Electricity traders, or cooled through Sprinkling Plate an automated Distribution and Feed Monitoring and warning in ca So any problem in equipment, temperature, water level, among others.La presente se refiere al campo técnico de la producción de derivados de la acuicultura, más especificadamente a un sistema y método automatizado y autosostenible para producción de derivados de la acuicultura (preferentemente la creación de tilapias), que tiene por objetivo, la producción de carne de pescados para alimentación humana, entre otras aplicaciones en el campo de la acuicultura. Siendo el sistema constituido de un invernadero (2), donde en su interior contiene un dique rectangular (1) dividido en reparticiones con un área de producción de los pescados (1A), donde en su interior se dispone de un sistema de oxigenado formado por difusores de disco de aire (3) o por mangueras micro porosas que reciben el aire del compresor radial (3A), y un área de decantación (1B) dividida en tres diques, que son dotados de un sistema de biofiltro (4) a través de los m