pi3k inhibitor salts and processes for their preparation

• 收藏
• 分享

专利权人:

INCYTE CORPORATION

发明人:

CHONGSHENG ERIC SHI,DAVID MELONI,JIACHENG ZHOU,LEI QIAO,LINGKAI WENG,MICHAEL XIA,PINGLI LIU,QIYAN LIN,TAI-YUEN YUE,VAQAR SHARIEF,WILLIAM FRIETZE,YOUNGCHUN PAN,ZHONGJIANG JIA

申请号：

BR112017018312

公开号：

BR112017018312A2

申请日:

2016.02.26

申请国别(地区):

BR

年份:

2018

代理人:

摘要：

The present application provides processes for preparing (r) -4- (3 - ((s) -1- (4-amino-3-methyl-1h-pyrazolo [3,4-d] pyrimidin-1-yl) ethyl) -5-chloro-2-ethoxy-6-fluorophenyl) pyrrolidin-2-one, which is useful as a phospho-inositide 3-kinase-delta (pi3kd) inhibitor, as well as a salt form and related intermediates.o presente pedido fornece processos para preparar (r)-4-(3-((s)-1-(4-amino-3-metil-1h-pirazolo[3,4-d]pirimidin-1-il)etil)-5-cloro-2-etóxi-6-fluorofenil)pirrolidin-2-ona, que é útil como um inibidor de fosfo-inositida 3-quinase-delta (pi3kd), bem como uma forma de sal e intermediários relacionados à mesma.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/