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Bispecific antibody binding to trailr2 and PSMA
专利权人:
发明人:
TAKAHASHI, NOBUAKI,高桥信明,高橋信明,NAKAYAMA, MAKOTO,中山真,中山真,TAKAGI SAYAKA,高木 沙耶加,高木 沙耶加
申请号:
TW105100603
公开号:
TW201632558A
申请日:
2016.01.08
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
The present invention relates to: a bispecific antibody including an antigen-binding domain that binds to TRAILR2 and an antigen-binding domain that binds to PSMA, or a fragment of said antibody a nucleic acid including a base sequence that encodes said antibody or said antibody fragment a recombinant vector including said nucleic acid a transformant strain including said recombinant vector a method for producing said bispecific antibody or said antibody fragment by using said transformant strain and a detection/measurement reagent, a diagnostic drug, and a therapeutic drug including said bispecific antibody or said antibody fragment.本發明係關於包含與TRAILR2結合之抗原結合區域及與PSMA結合之抗原結合區域的雙專一性抗體或該抗體片段、具有編碼該抗體或該抗體片段之鹼基序列的核酸、包含該核酸之重組載體、包含該重組載體之轉形株、使用該轉形株之該雙專一性抗體或該抗體片段之製造方法、以及包含該雙專一性抗體或該抗體片段之檢測或測定試劑、診斷藥及治療藥。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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