SCHEER, Justin,SPIESS, Christoph,YANSURA, Daniel G.
申请号：
DK11718831
公开号：
DK2560683T3
申请日:
2011.04.22
申请国别(地区):
DK
年份:
2017
代理人:
摘要：
Described herein are methods for the efficient production of antibodies and other multimeric protein complexes (collectively referred to herein as heteromultimeric proteins) capable of specifically binding to more than one target. The targets may be, for example, different epitopes on a single molecule or located on different molecules. The methods combine efficient, high gene expression level, appropriate assembly, and ease of purification for the heteromultimeric proteins. The invention also provides methods of using these heteromultimeric proteins, and compositions, kits and articles of manufacture comprising these antibodies.
