MORIYA, MINORU,守谷实,守谷實,YASUHARA, AKITO,安原明登,SAKAGAMI, KAZUNARI,坂上一成,OHTA, HIROSHI,太田裕之,ABE, KUMI,阿部公美,YAMAMOTO, SHUJI,山本修资,山本修資,ARAKI, YUKO,荒木裕子,URABE, HIROKI,浦部洋树,浦部洋樹,SUN, X
申请号：
TW100133468
公开号：
TW201225957A
申请日:
2011.09.16
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
The purpose of the present invention is to provide a novel compound, or a medically acceptable salt thereof, which is useful in the prevention or treatment of conditions such as schizophrenia, Alzheimer's disease, cognitive disorders, dementia, anxiety disorders (such as general anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder, specific phobias, and acute stress disorder), depression, drug dependency, convulsions, tremors, aches, or sleep disorders, on the basis of having inhibitory action on glycine uptake. A compound represented by formula [1] or a medically acceptable salt thereof.本發明係以提供對於以甘胺酸吸收阻礙作用為準的精神分裂症、阿茲海默病、認知功能障礙、失智症、焦慮障礙(全般性焦慮障礙、恐慌障礙、強迫性障礙、社會焦慮障礙、創傷後壓力心理障礙、特定恐懼症、急性壓力障礙等)、憂鬱症、藥物依存、痙攣、手震、疼痛，或睡眠障礙等疾病的預防或治療上有用之新穎化合物或其醫藥上可被許可的鹽為目的。【化1】所示化合物或其醫藥上可被許可的鹽。
