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RNA VIRUS VECTORS CARRYING DAI AND RIPK3
专利权人:
Institute For Cancer Research d/b/a The Research Institute Of Fox Chase Cancer Center
发明人:
Siddharth Balachandran,Roshan Thapa
申请号:
US16315420
公开号:
US20190211359A1
申请日:
2017.07.05
申请国别(地区):
US
年份:
2019
代理人:
摘要:
RNA virus vectors comprising a gene encoding the DNA-dependent activator of interferon-regulatory factors (DAI) protein, and optionally further comprising a gene encoding the receptor-interacting serine/threonine-protein kinase 3 (RIPK3) may be used therapeutically to induce cell death, as well as an inflammatory immune response, against tumors and virally-infected cells.
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