GREG NITZEL,PHILLIP WAYNE HAYES,MICHAEL B. ROOF,MARC ALLAN EICHMEYER,MERRILL LYNN SCHAEFFER
申请号:
PT06164854
公开号:
PT2371385E
申请日:
2006.12.28
申请国别(地区):
PT
年份:
2015
代理人:
摘要:
The present invention relates to an immunogenic composition that comprises a porcine circovirus type 2 (PCV2) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV2 infection. Preferably, they include lymphadenopathy, lymphoid depletion and/or multinucleated/giant histiocytes. Moreover, the clinical symptoms include lymphadenopathy in combination with one or a multiple of the following symptoms in pigs: (1) interstitial pneumonia with interlobular edema, (2) cutaneous pallor or icterus, (3) mottled atrophic livers, (4) gastric ulcers, (5) nephritis and (6) reproductive disorders, e.g. abortion, stillbirths, mummies, etc. Furthermore the clinical symptoms include Pia like lesions, normally known to be associated with Lawsonia intracellularis infections.