The present invention relates to a prosthetic valve assembly for replacing a deficient native aortic valve, comprising:a metallic frame formed with intercrossing bars, said frame being collapsible to a compressed diameter for advancement through a patients body channel using a catheterization technique, said frame being expandable to an expanded position for implantation within said deficient native aortic valvea collapsible valvular structure having a base and an upper part, said base of said valvular structure fastened to said frame, said valvular structure formed of pericardial tissue for permitting blood flow in one direction andguiding means extending from said base to said upper part of said valvular structure for creating stiffened zones which induce said valvular structure to follow a patterned movement when moving from a closed state to an open state.