The present invention relates to a topical dermatological/pharmaceutical composition comprising BPO wherein the composition is a wash composition with desirable tolerance, stability and foaming properties. The composition comprises: a) Benzoyl peroxide (BPO), b) At least one anionic and/or non-ionic surfactants, selected from Zinc coceth sulfate； sodium cocoyl isethionate, sodium lauroyl isethionate, C14-C16 a- olefinsulfonates preferably its sodium salt and decyl glucoside, c) Zinc gluconate, d) Dipotassium glycyrrhizate, e) An oily phase, f) An aqueous phase, g) At least one non-ionic emulsifier from the family of sugar ester derivatives, and/ or polyglycerol esters and / or gemini surfactants. The composition is preferably in the form of an oil in water emulsion. The invention also concerns the use of such composition for the treatment of dermatological disorders, and in particular in the treatment of acne.
