KIM, Hong-Kee,SHIN, Ho Chul,Lee, Yoon-Jung,LEE, Ho Soon,LEE, Ji-Hye,KANG, Seok-chan,KIM, Hun-Taek
申请号：
EP14871697
公开号：
EP3085384A4
申请日:
2014.12.16
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to a pharmaceutical composition with improved stability, containing, as active ingredients, factor VII and transferrin, wherein the transferrin contains a fusion protein linked to the C-terminal of factor VII and trehalose or glycine as a bulking agent. The composition can stably store factor VII and a modification thereof at room temperature for a long time, and thus can be used as a useful therapeutic agent for patients suffering from hemophilia or congenital factor VII deficiency.
