Barry, Simon,Krumbiegel, Doreen,Eastaff-Leung, Nicola Ga-Ling,Nicholson, Ian Cameron,Zola, Heddy
申请号:
AU2011241483
公开号:
AU2011241483B2
申请日:
2011.04.18
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present disclosure provides an isolated protein comprising at least one antibody variable region that is capable of binding to peptidase inhibitor 16 (PI16), wherein the protein is also capable of competitively inhibiting binding of an antibody produced by a hybridoma designated CRCBT-02-001 deposited with the ATCC under Accession Number PTA-10685 to PI16. The present invention also provides use of the protein, e.g., in diagnosis, therapy or to isolate cells, preferably Treg cells.