Keith P. Johnston,Maria Andrea Mazuski,Joshua Engstrom,Miguel Angelo Rodrigues
申请号：
US14297403
公开号：
US20140378370A1
申请日:
2014.06.05
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invent ion also provides a high concentration low viscosity suspension of an pharmaceutically acceptable solvent with one or more sub-micron or micron-sized non-crystalline particles comprising one or more proteins or peptides. Optionally one or more additives in the pharmaceutically acceptable solvent to form a high concentration low viscosity suspension with a concentration of at least 20 mg/ml and a solution viscosity of between 2 and 100 centipoise that is suspendable upon shaking or agitation, wherein upon delivery the one or more sub-micron or micron-sized peptides dissolves and do not form peptide aggregates syringeable through a 21 to 27-gauge needle.
