ARNSI D'INTERLEUKINE HUMAINE 6, VECTEUR CAR-T D'EXPRESSION RECOMBINANTE, ET LEUR PROCÉDÉ DE CONSTRUCTION ET UTILISATION

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专利权人:

Shanghai Unicar-therapy Bio-Medicine Technology Co.; Ltd

发明人:

QI, Wei,KANG, Liqing,YU, Lei,XIA, Ronghua

申请号：

EP16918621

公开号：

EP3505629A4

申请日:

2016.11.10

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Provided are a siRNA of the human interleukin 6, a recombinant expression CAR-T vector, and a construction method and a use thereof. The siRNA can be used in the treatment of acute B-cell lymphocytic leukemia with CAR19-T for eliminating or alleviating the symptoms of cytokine release syndrome (CRS), and can also be used for alleviating the CRS symptoms caused by treating tumours with CAR-T and even can also be used for alleviating CRS caused by other types of treatment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/