JACKSON, SIMON MARK,WALKER, NIGEL PELHAM CLINTON,PIPER, DEREK EVAN,SHAN, BEI,SHEN, WENYAN,CHAN, JOYCE CHI YEE,KING, CHADWICK TERENCE,KETCHEM, RANDAL ROBERT,MEHLIN, CHRISTOPHER,CARABEO, TERESA ARAZAS,Q
申请号：
PE0008832013
公开号：
PE02202014A1
申请日:
2008.08.22
申请国别(地区):
PE
年份:
2014
代理人:
摘要：
Referring to a Binding Protein Antigen neutralizing noncompetitive LDLR comprises an Amino Acid Sequence SEQ ID N\ufffd1, where Binding Protein that binds selectively to proprotein Convertase subtilisin \/ kexina Type 9 (PCSK9). It also relates to an Antibody and a preparation method.This Binding Protein is useful in the treatment of Hypercholesterolemia, among othersREFERIDA A UNA PROTEINA DE UNION A ANTIGENO NEUTRALIZADORA NO COMPETITIVA DE LDLR QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS DE SEQ ID N�1, DONDE DICHA PROTEINA DE UNION SE UNE SELECTIVAMENTE A PROPROTEINA CONVERTASA SUBTILISINA/KEXINA TIPO 9 (PCSK9). TAMBIEN ESTA REFERIDA A UN ANTICUERPO Y A UN METODO DE PREPARACION. DICHA PROTEINA DE UNION ES UTIL EN EL TRATAMIENTO DE LA HIPERCOLESTEROLEMIA, ENTRE OTROS
