A urinary tubing for mitigating against microbial migration, as well as a system and method for forming and maintaining a closed-system of urinary tubing are described. Such tubing may comprise: a first terminal end a second terminal end, longitudinally opposing the first terminal end a wettable region, which may comprise a surface which may be wetted by a fluid flowing within the tubing and a means for mitigating against microbial migration in a direction opposite of intended flow. Such means may be selected from one or more of the group comprising at least one check-valve, at least one biofilm abater, and the wettable region treated with an antimicrobial coating. Such means may be located within the tubing, at the first terminal end, or at the second terminal end.
