SCHIEMANN, Kai,EMDE, Ulrich,FINSINGER, Dirk,AMENDT, Christiane,HEISS, Nina,ZENKE, Frank
申请号:
ES06840909
公开号:
ES2566729T3
申请日:
2006.05.17
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Compounds of the formula I ** Formula ** wherein W is CH or N, R1, R2, R3 are, independently of each other, H, A, aryl, heteroaryl, Hal, - (CY2) n-SA, - (CY2) n-SCF3, - (CY2) n- SCN, - (CY2) n-CF3, - (CY2) n-OCF3, R, NR-NR2, X (CY2) nXR, X (CY2) nY, ( CY2) ncycloalkyl, (CY2) nCH>; = CH2, cycloalkyl, -SCH3, -SCN, -CF3, -OCF3, -OA, (CY2) n-OH, - (CY2) n-CO2R, - (CY2) n- CN, - (CY2) n-Hal, - (CY2) nY, - (CY2) n-NR2, (CY2) n-OA, (CY2) n-OCOA, -SCF3, (CY2) n-CONR2, - ( CY2) n-NHCOA, - (CY2) n- NHSO2A, SF5, Si (CH3) 3, CO- (CY2) n-CH3, - (CY2) nN-pyrolidone, (CH2) nNRCOOR, NRCOOR, NCO, (CH2 ) nCOOR, NCOOR, (CH2) nOH, NR (CH2) nNR2, C (OH) R2, NR (CH2) nOR, NCOR, (CH2) naryl, (CH2) nheteroaryl, (CH2) nR1, (CH2) nX ( CH2) Naryl, (CH2) nX (CH2) nheteroaryl, (CH2) nCONR2, XCONR (CH2) nNR2, N [(CH2) nXCOOR] CO (CH2) Naryl, N [(CH2) nXR] CO (CH2) Naryl, N [(CH2) nXR] CO (CH2) nXaryl, N [(CH2) nXR] SO2 (CH2) naryl, N [(CH2) nNRCOOR] CO (CH2) naryl, N [(CH2) nNR2] CO (CH2) Naryl, N [(CH2) nNR2] CO (CH2) nNRaryl, N [(CH2) nNR2] SO2 (CH2) Naryl, N [(CH2) nXR] CO (CH2) nheteroaryl, N [(CH2) n XR] CO (CH2) nXheteroaryl, COaryl, SO2aryl, N [(CH2) nXR] SO2 (CH2) nheteroaryl, N [(CH2) nNRCOOR] CO (CH2) nheteroaryl, N [(CH2) nNR2] CO (CH2) nheteroaryl , N [(CH2) nNR2] CO (CH2) nNRheteroaryl, R1 and R3 are also together -N- C (CF3)>; = N-, -N-CR>; = N-, -NN>; = N- and where Non-adjacent CY2 groups can also be replaced by X, Y is H, A, Hal, OR, E-R1, E is -NR1SO2-, -SO2NR1, -CONR1, -NR1CO-, -COO-, OOC-, CO , -SO2-, -X-, NR1CONR1, -OCONR1, -NR1COO-, -CSNR1, NR1CS-, -NR1CSNR1-, -SCONR1-, -NR1COS-, -OCSNR1, NR1CSO-, SCSNR1, -NR1CSS or a single link , A is cycloalkyl or unbranched or branched alkyl with 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10 C atoms, where one or more H atoms can be replaced by Hal, Aryl is phenyl, naphthyl or biphenyl unsubstituted or mono-, di- or trisubstituted with Hal, A, OH, OA, NH2, NO2, CN, COOH, COOA, CONH2, NHCOA, NHCONH2, NHSO2A, CHO, COA, SO2NH2, SO2A, -CH2-COOH o