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Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
专利权人:
TRANSMEDICS INC.
发明人:
HASSANEIN WALEED,KHAYAL TAMER,ELBETANONY AHMED,LEZBERG PAUL,CECERE GIOVANNI,SOUSA DENNIS,HANSEN ELIZABETH
申请号:
NZ62557508
公开号:
NZ625575A
申请日:
2008.04.24
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is an organ care system configured to perfuse an ex vivo heart, the system comprising: -a chassis; -an organ chamber assembly mounted to the chassis for containing the heart during perfusion, the organ chamber comprising: –a fluid conduit with a first interface configured to connect to an aorta of the heart and -a second interface configured to connect to a pulmonary vein of the heart; –a Lactate A sensor configured to measure lactate in the first interface; –a Lactate V sensor configured to measure lactate in the second interface; and -a processor configured to calculate a Lactate V-A differential using lactate values measured by the Lactate A sensor and the Lactate V sensor, wherein the processor is configured to calculate Lactate V-A differential at two different times, wherein the processor is further configured to calculate a change in V-A differential between the two different times to correlate a change between the V-A lactate differentials over time with suitability of the heart for transplantation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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