ALBAEK, Nanna,HEDTJÄRN, Maj,LINDHOLM, Marie,NIELSEN, Niels Fisker,PETRI, Andreas,RAVN, Jacob
申请号:
HUE14739708
公开号:
HUE048738T2
申请日:
2014.06.27
申请国别(地区):
HU
年份:
2020
代理人:
摘要:
The present invention relates to oligomeric compounds and conjugates thereof that target Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) PCSK9 mRNA in a cell, leading to reduced expression of PCSK9. Reduction of PCSK9 expression is beneficial for a range of medical disorders, such as hypercholesterolemia and related disorders.