Dong Liu;Joel D. Moore;Deqiang Niu;Ying Sun;Guoyou Xu;Zhe Wang;Datong Tang;Yonghua Gai;Yat Sun Or
发明人:
Deqiang Niu,Dong Liu,Joel D. Moore,Guoyou Xu,Ying Sun,Yonghua Gai,Datong Tang,Yat Sun Or,Zhe Wang
申请号：
US11768712
公开号：
US08501681B2
申请日:
2007.06.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof:which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
