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FFA1 (GPR40) UTILISÉ COMME CIBLE THÉRAPEUTIQUE POUR DES MALADIES OU DES TROUBLES NEURONAUX LIÉS À L'ANGIOGENÈSE
专利权人:
Children's Medical Center Corporation
发明人:
SMITH, Lois,JOYAL, Jean-sebastien
申请号:
EP17753944
公开号:
EP3416726A4
申请日:
2017.02.17
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The instant invention provides methods and compositions related to discovery of Free Fatty Acid Receptor 1 (FFA1) as a therapeutic target for treatment or prevention of diseases or disorders of neurons that are characterized by angiogenesis, or of vascular diseases of the eye, retinal degeneration and/or tumors more generally. Therapeutic and/or prophylactic uses and compositions of known FFA1 inhibitors, including small molecules and nucleic acid agents, are described. Methods for identification of novel FFA1 inhibitors are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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