Huang, Eric Yi-Chun,Tse, Sze-Wah,Iacovelli, Jared,McKinney, Kristine,Valiante, Nicholas
申请号:
AU2018214556
公开号:
AU2018214556A1
申请日:
2018.02.01
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The disclosure features immunomodulatory therapeutic compositions of an mRNA encoding an activating oncogene mutation peptide and an mRNA encoding a polypeptide that enhances immune responses to the activating oncogene mutation peptide, for example an mRNA encoding an immune potentiator. The disclosure also features methods of using the same, for example, to stimulate anti-cancer immune responses.