BRUNO BUJOLI,JEAN MICHEL BOULER,PASCAL JANVIER,IBRAHIM KHAIROUN,VERENA SCHITZLER,CHARLOTTE MILLIER
申请号：
IN6750/DELNP/2011
公开号：
IN284760B
申请日:
2011.09.02
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to a galiiated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I): Ca(10.5-1.5x)Gax(PO4)7 (I) wherein 0 < x < 1 and the salts, hydrates and mixtures thereof and/or a calcium deficient apatite structure with in particular a (Ca + Ga)/P molar ratio in the range of 1.3 to 1.67, and a gallium content up to 4.5 % by weight. It also relates to processes of preparation of such materials and uses thereof, in particular as dental or bony implants. It further relates to a kit comprising a galiiated calcium-phosphate biomaterial in combination with a fluid component. It finally relates to methods of use of the galiiated calcium-phosphate biomaterial, notably for III) ions increase radio-opacity after bone implantation and can be released for inhibiting bone resorption.
