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Polyvalent Fusion Protein Vaccine Against Influenza
专利权人:
发明人:
Ilya Vladimirovich Dukhovlinov,Anton Iosifovich Orlov,Ljudmila Markovna Tsybalova,Oleg Ivanovich Kiselev
申请号:
US14768107
公开号:
US20150374814A1
申请日:
2014.02.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The problem to be solved: absence of safe efficient universal vaccine against influenza. The solution: The vaccine based on the fusion protein consisting of antigenic determinants of haemagglutinins of influenza A and B viruses and flagellin fragments functioning as safe adjuvant (SEQ ID NO:1) joined via flexible hinges is given which can be used for prophylaxis of influenza caused by existing influenza A and B strains as well as by possible reassortants. Safety, efficacy, polyvalence and preventive effect have been demonstrated. Usage of the present vaccine will allow to provide a universal protection against influenza.
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